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Forward from: NBME | CMS
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🎉 FREE NBME Self-Assessment! 🎉

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Forward from: NBME | CMS
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🎉 FREE NBME Self-Assessment! 🎉

Get NBME Form 25 at no cost—limited-time offer!

⏰ Don't Miss Out!

👉 Sign Up Now: 👇👇👇👇👇👇👇

🔗 nbmeway.com/nbme/signup.php

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💬 @NBMECMS


Forward from: USMLE RECALLS STEP 1 AND 2 2021
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Forward from: Unknown


A 54-year-old man is brought to the office by his friend because of worsening memory impairment over the past several months. The patient is also withdrawn and not focused during conversations. He is slow to answer questions or carry out instructions. The patient has a prolonged history of HIV infection and has had several opportunistic infections due to inconsistent antiretroviral medication use. On physical examination, he is alert and oriented. Muscle strength, deep tendon reflexes, and sensation are normal. MRI of the head shows diffuse cerebral atrophy with no focal mass lesions or areas of demyelination.


Forward from: (NBME) National Board Medical Exams
Which NBME would you like to get first?
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  •   NBME 18
  •   Nbme 25
  •   Nbme 26
  •   Nbme 27
  •   Nbme 28
  •   NBME 29
  •   NBME 30
8320 votes


Forward from: (NBME) National Board Medical Exams
Would you like to get free online NBME?
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  •   Yes
  •   No
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Forward from: (NBME) National Board Medical Exams
Which step are you preparing?
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  •   Step 1
  •   Step 2
  •   Step 3
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Forward from: Pathology Videos & Books 2021
42. A burn wound characterized by the absence of painful sensation, bleeding, or capillary refilling is best classified as:
Poll
  •   □First degree
  •   □Moderate to severe
  •   □Second degree
  •   □Midlevel
  •   Full thickness
1087 votes


Forward from: Pathology Videos & Books 2021
50. An amputated foot of a diabetic will most likely show:
Poll
  •   a) Neoplasia
  •   b) Gangrenous Necrosis
  •   c) Coagulopathy
  •   d) Hemosiderosis
  •   e) Caseation
1142 votes


Forward from: Board and beyond Videos
Answer E (correct answer): The question shows a Michaelis-Menten curve for an enzymatic reaction. Maximum velocity of enzymatic conversion of alcohol to acetaldehyde occurs at an ethanol concentration of about 0.08g/dl. At concentrations above this level, metabolism of ethanol into acetaldehyde will occur at a constant rate. Thus, when the blood alcohol level increases from 0.08 to O.lOg/dL there will be no change in rate of aceta!dehyde formation.


Forward from: Board and beyond Videos
If he increases his blood alcohol level to 0.10 g/dl, which of the following will occur?
Poll
  •   A) Binding affinity of ethanol to liver enzymes will increase
  •   B) Binding affinity of ethanol to liver enzymes will decrease
  •   C) Acetaldehyde formation will increase
  •   D) Acetaldehyde formation will decrease
  •   E) No change in acetaldehyde formation rate will occur
381 votes


Forward from: Board and beyond Videos


Forward from: Board and beyond Videos
Answer C (correct answer): The graph is a Lineweaver Burk plot for the two enzymes, A and 8. Lineweaver Burk plots are a variant of Michaelis­
Menten saturation curves that make the data linear rather than curved.


Forward from: Board and beyond Videos
Which of the following is correct?
Poll
  •   A) Population A has a higher capacity to metabolize acetaldehyde
  •   B) Population B has a higher capacity to metabolize acetaldehyde
  •   C) Enzyme A binds more avidly to acetaldehyde
  •   D) Enzyme B binds mo
230 votes


Forward from: Board and beyond Videos


Forward from: Board and beyond Videos
Answer B (correct answer): The Michaelis constant, Km, represents how avidly an enzyme binds to substrate. The lower the Km value, the more easily
the enzyme binds substrate. Systems with a low Km rapidly reach Vrnax because the enzyme is highly effective at binding substrate. Conversely,
enzymes with a high Km require large amounts of substrate to reach Vmax. ALDHC has a much lower Km compared to ALDHJ. Thus, ALDHC binds to
substrate with higher affinity.


Forward from: Board and beyond Videos
Which of the following is correct?
Poll
  •   A) Afinity of substrate binding to ALDHJ is higher
  •   B) ALDHC binds to substrate with higher affinity
  •   C) ALDHJ is more efficient at catabolism
  •   D) ALDHC enzyme has less rapid turnover
  •   E) ALDHJ enzym
208 votes


Forward from: Board and beyond Videos

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