Genome Analysis

🔴 RNA-seq Data Analysis: A Practical Approach
(ebook)

🔷 The State of the Art in Transcriptome Analysis
RNA sequencing (RNA-seq) data offers unprecedented information about the transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. RNA-seq Data Analysis: A Practical Approach enables researchers to examine differential expression at gene, exon, and transcript levels and to discover novel genes, transcripts, and whole transcriptomes.

Balanced Coverage of Theory and Practice
Each chapter starts with theoretical background, followed by descriptions of relevant analysis tools and practical examples. Accessible to both bioinformaticians and nonprogramming wet lab scientists, the examples illustrate the use of command-line tools, R, and other open source tools, such as the graphical Chipster software.

The Tools and Methods to Get Started in Your Lab
Taking readers through the whole data analysis workflow, this self-contained guide provides a detailed overview of the main RNA-seq data analysis methods and explains how to use them in practice. It is suitable for researchers from a wide variety of backgrounds, including biology, medicine, genetics, and computer science. The book can also be used in a graduate or advanced undergraduate course.

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🔴 Bioinformatics: A Practical Handbook of Next Generation Sequencing and Its Applications (ebook)


🔷 Rapid technological developments have led to increasingly efficient sequencing approaches. Next Generation Sequencing (NGS) is increasingly common and has become cost-effective, generating an explosion of sequenced data that need to be analyzed. The skills required to apply computational analysis to target research on a wide range of applications that include identifying causes of cancer, vaccine design, new antibiotics, drug development, personalized medicine and higher crop yields in agriculture are highly sought after.
This invaluable book provides step-by-step guides to complex topics that make it easy for readers to perform essential analyses from raw sequenced data to answering important biological questions. It is an excellent hands-on material for teachers who conduct courses in bioinformatics and as a reference material for professionals. The chapters are written to be standalone recipes making it suitable for readers who wish to self-learn selected topics. Readers will gain skills necessary to work on sequenced data from NGS platforms and hence making themselves more attractive to employers who need skilled bioinformaticians to handle the deluge of data.

🔷 Readership: It is a necessary companion for undergraduates, graduate students, researchers and anyone interested in the exponentially growing field of bioinformatics.

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🔴 Register for the webinar:
Implementing and Scaling a Rapid Whole Genome Sequencing Test at Rady Children's Institute for Genomic Medicine

🔹 March 21, 2019
1PM (EST) / 10AM (PT)

🔷 In this presentation, Dr. Katarzyna Ellsworth, Associate Laboratory Director at Rady Children's Institute for Genomic Medicine, will discuss the launching and scaling of clinical NGS testing in a children’s hospital environment, utilizing Fabric Enterprise for the rapid interpretation of genomic data to decrease turnaround time and increase diagnostic yield. Rady is advancing rapid whole genome testing as a first-line test to diagnose critically ill children in the NICU and PICU.

Register here: https://bit.ly/2UwDWOM

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🔴Optimizing ES–based diagnostics of a clinically diverse patient population

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🔴 Webinar: Rapid Whole Genome Sequencing in the NICU and PICU Decreases Infant Morbidity and Mortality

Presented By: Stephen Kingsmore, MD - President and CEO, Rady Children's Institute for Genomic Medicine

Webinar Abstract: Rare disease affects 30 million people in the United States, with nearly 50% of cases affecting children. Because nearly 80% of rare diseases are genetic, advancements in genomic testing are key to pinpointing an accurate diagnosis. The Rady Children’s Institute for Genomic Medicine has engineered a Whole Genome Sequencing process to rapidly decode, analyze and interpret the root causes of rare genetic disorders in newborns and children in intensive care in a matter of days. RCIGM president and CEO Stephen Kingsmore, MD, DSc, discusses how his team is working to equip clinicians with this critical information to facilitate medical decision making.

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