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Образование
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Correct Answer - A
Ans. is 'a' i.e., Homogentisic acid

Alkaptonuria
It is due to deficiency of homogentisate oxidase. As a
result homogentisic acid (homogentisate) is excreted
execessively in urine. There are three important characteristic
features in alkaptonuria?

1. Urine becomes dark after being exposed to airQ. It is due
spontaneous oxidation of homogentisate into benzoquinone
acetate, which polymerse to form black-brown pigment alkapton which imparts a characteristic black-brown colour to urine.

2. Alkapton deposition occurs in sclera, ear, nose, cheeks and
intervertebral disc space. A condition called ochronosis. There
may be calcification of intervertebral discs Q.

3. Onchronosis arthritis affecting shoulder, hips, knee.

4. Benedict's test is strongly positive in urine and so is the ferric chloride (Pea) testQ. Benedict's reagent gives a greenish brown precipitate with brownish black supernatent. Fehling's reagent (FeC13 ) gives blue green colour

@biochemistry_videos


Ochronosis is due to accumulation of #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.Homogentisic acid
  •   B.Phenylpyruvate
  •   C.Xanthourate
  •   D.Glycoxylate
3647 голосов


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Km value is defined as: #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.Substrate concentration at Vmax/2
  •   B.Substrate concentration of twice Vmax
  •   C.Substrate concentration of thrice Vmax
  •   D.Substrate concentration of one third Vmax
3578 голосов


In starvation, nitrogen is carried from muscle to liver and kidney by: #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.Alanine
  •   B.Aspartic and serine
  •   C.Glycine
  •   D.Asparginase
4145 голосов


Correct Answer - A
Ans. is 'a' i.e., Degradation of collagen

Degradation of collagen and other ECM (extracellular matrix)
proteins is achieved by matrix metalloproteinases (MMPs).

MMPs is a family of enzymes that have in common a 180-residue
zinc protease domain.

Matrix metalloproteinases include :-
Interstitial collagenase (MMP-1, 2, and 3) : Cleave the fibrillar
collagen types I, II and III.
Gelatinases (MMP-2 and 9) : Degrade amorphous collagen and
fibronectin.

Stromelysins (MMP-3, 10 and 11) : Act on proteoglycans, laminin,
fibronectin and amorphous collagen.

Membrane-bound MMPs (ADAMs) : Cleave membrane-bound precursor forms of TNF and TGF-a, releasing the active molecule.


@biochemistry_videos


Action of metalloproteinase ? #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.Degradation of collagen
  •   B.Polymerazination of collagen
  •   C.Oxidation of collagen
  •   D.Stimulation of collagen
3618 голосов


Richest source of vitamin B12 ? #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.Meat
  •   B.green leafy vegetables
  •   C.Corn oil
  •   D.Sunflower oil
5519 голосов


FIGLU excretion test is used for assessment of deficiency of ? #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.Vitamin B12
  •   B.Folic acid
  •   C.Pyridoxine
  •   D.Niacin
4638 голосов


Correct Answer - B
Ans. is 'b' i.e., Pyridoxin

@/biochemistry_videos


Deficiency of which vitamin causes excretion of xantheurenic acid in urine ? #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.vit B12
  •   B.Pyridoxine
  •   C.Niacin
  •   D.Folic acid
5004 голосов


Correct Answer - D
Ans. is 'd' i.e., All of the above
Trinucleotide repeat mutation

In this type of mutation a codon (i.e. trinucleotide sequence)
undergoes amplification and the same codon is repeated
continuously so many times in the chain.

Diseases associated with trinucleotide repeat mutation are
Huntington's disease (CAG repeat), Spinocerebellar ataxia (CAG
repeat), friedreich ataxia (GAA repeat), fragile-X-syndrome (GGG or
GCC repeat), dystrophia myotonica (CTG/CUG repeat), X-linked
spinobulbar muscular atrophy (CAG repeat) and dentorubral
pallidolusian atrophy (CAG repeat)

@biochemistry_videos


Which of the following is an example of Trinucleotide repeat mutation ? #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.Huntigtson chorea
  •   B.Fragile x syndrome
  •   C.Friedrich ataxia
  •   D.All of the above
4054 голосов


Correct Answer - D
Ans. is 'd' i.e., Riboflavin
Riboflavin and niacin are involved in redox (reduction and oxidation)
reactions.

@biochemistry_videos


Which Vitamin is involved in Redox reactions #PYQ#FMGE#NEETPG#INICET
Опрос
  •   A.Biotin
  •   B.Pyridoxine
  •   C.Folic acid
  •   D.Riboflavin
5468 голосов

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