Patients with Tetralogy of Fallot often experience "tet spells" which may be caused by crying, fever, and exercise due to exacerbation of
RV outflow tract obstructionPatients with Tetralogy of Fallot may
squat in response to cyanotic spells, which
decreases right-to-left shunting by increasing systemic vascular resistance (SVR)
inhaled O2 may help stimulate pulmonary vasodilation and systemic vasoconstriction, which can further decrease right-to-left shunting
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