A 35-year-old man with no previous psychiatric history is referred by his family physician for psychiatric evaluation. The family physician has been following the man for mild hyperlipidemia, which is currently being successfully treated with dietary changes alone. The man reports that he has been happily married for 10 years and has two children. He has been working as an accountant and has generally enjoyed his job. About 2 months ago, with no obvious precipitating event, he says, the man began to feel very blue, with a drop in his desire to play with his children and to compete in his usual volleyball league games. He reports that he has lost most of his libido and is having difficulty sleeping, with earlymorning wakening. He reports that his appetite has become very poor over the past 2 months, and he estimates that he has lost 10 lbs over that time.