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Open Longevity ENG

@OpenLongevity_en
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Transhumanism and social landscape of life extension. Also Open Longevity news.
Chat: https://t.me/OpenLongevityChat
WebSite: openlongevity.org
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@KobelevS

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Open Longevity ENG

19 Feb 2021, 23:02

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Joao Pedro de Magalhaes, one of the coolest people in aging research, is offering a job: “I am looking for an assistant who can occasionally help me, for example preparing various documents. Good communication and computer skills are essential. Can be based anywhere in the world but proficiency in English is required. A science background would be a plus but is not essential. Please message me if interested”.
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Open Longevity ENG

18 Feb 2021, 17:35

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#Longevity_101
If you’re new in the field and want some good quality basic info, here’s something to start with. An interview with Luigi Ferrucci. He is a Scientific Director of NIA (National Institute of Aging, which is a part of National Institute of Health, USA). Basically it’s one of the biggest (if not the biggest) institutes working on the problem. And as much as we are not happy with the situation in aging research in the World (USA included) in general, Ferrucci is truly a professional and this interview is a good read. Fresh too—just of Jan 21, 2021.
Reflections on aging research from within the National Institute on Aging
The NIA (part of the NIH) is one of the leading funders of aging and age-related disease research worldwide. Last fall, Nature Aging spoke to Luigi Ferrucci, its Scientific Director since 2011, to get his thoughts on the field and learn about the institute’s agenda and future plans for intramural an...
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Open Longevity ENG

17 Feb 2021, 10:06

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That being said, «Lifespan is running the news outlet focused on aging research for over 5 years now. During this time we faced many difficult questions that eventually lead us to develop our own Ethics code. :) Today we are sharing it with the longevity community in the hope that it will allow our fellow journalists to be more effective in the mission of informing the public about rejuvenation biotechnologies».
Developing Our Ethics Code of Longevity Journalism | Lifespan.io
When Lifespan.io was started in 2014 as a crowdfunding platform, we didn’t really know that we would become a news outlet covering longevity research. We […]
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Open Longevity ENG

17 Feb 2021, 03:04

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Leon Pesha
Help! Can someone write an article or even a book «Ageless: we are NOT there yet and not gonna be for a while if we continue sensationalist journalism and entrepreneurship». I am very serious this sensationalist crap is one key reason we will all die of old age soon. I see one chapter per «approach»... and yes, I can back it all up with literature and expert opinions.
1. Telomeres. Long disproven. Few cell types divide enough to eat into telomeres, other factors kill us long before then.
2. Senolytics. Nonsense. Noone knows what is senescent cell or whether they even exist. Not to mention no senolytics have been proven in any animals.
3. GDF15. Actually up not down with age...
4. NAD+... mild stimulant, mildly carcenogenic, no other effect
5. Resveratrol... red wine, old debunked nonsense
6. Methylation clocks and «biological age» never shown to work in reverse (fixing the «clock» does not make you younger).

and then there is Andrew Stelle... not a biologist, not a scientist... just talking out his ass.
Do we have to age?
The biologist Andrew Steele thinks ageing is a disease that can be treated. But if we had a cure for getting old, what would that mean for us?
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Open Longevity ENG

16 Feb 2021, 15:59

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«She was struggling. Her science was fantastic, but she was less adept at the competitive game of science. She tried again and again to win grants, and each time, her applications were rejected.
Eventually, in the mid-1990s, she suffered the academic indignity of demotion, meaning she was taken off the academic ladder that leads to becoming a professor. The university stopped supporting her. Academic science failed Karikó. But she had moved to the private sector. And now, I watch in awe, like the rest of the world, as the technology she helped developed leads to one of the most spectacular victories in the history of science - a vaccine for a deadly pandemic developed in less than one year».
https://www.wbur.org/commonhealth/2021/02/12/brutal-science-system-mrna-pioneer?fbclid=IwAR0bFU7RkililOGe8gKgmYlOiCl8D-spHQO6fmd03UDZthvruDeo0zMko94
How Our Brutal Science System Almost Cost Us A Pioneer Of mRNA Vaccines
A doctor who witnessed the tribulations of mRNA vaccine pioneer Katalin Karikó warns that science is naturally hard, but the system that puts make-or-break financial pressures on American scientists makes it even harder.
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Open Longevity ENG

14 Feb 2021, 22:57

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Open Longevity ENG

14 Feb 2021, 22:56

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Open Longevity ENG

8 Feb 2021, 09:46

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Elena Milova
Some news. :) I am appointed a Chief Operating Officer of Lifespan.io, which is a huge honor and responsibility. :)

The Board accepted my plan of development and I am leading its implementation. We are currently upgrading our infrastructure so there will be several job opportunities opening up in the next month.

We are currently looking for an experienced SMM, you may find the job offer here. Next in line is an event manager, then an IT coordinator. Stay tuned!
Lifespan.io Announces Promotions and Expansion | Lifespan.io
2020 was a year of tremendous growth for Lifespan.io. As many of you have likely noticed, our news outlet team has hired two more excellent science journalists, Arkadi Mazin and Greg Gillipsie. […]
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Open Longevity ENG

17 Jan 2021, 10:04

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Open Longevity ENG

11 Jan 2021, 14:08

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Open Longevity ENG

11 Jan 2021, 14:08

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Open Longevity ENG

22 Mar 2020, 20:02

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Peter Fedichev
it's hard to get attention by posting anything that is not COVID-19 related these days, but: they say, that you do not have a good drug if it's not been killed at least three times (during the development). Enjoy reading the historical review about the discovery and development of statins by Akira Endo, the very same guy who discovered statins, proved the drugs working in humans, got his project killed for a wrong reason and did not get the Nobel Prize (others did).

His employer had all the necessary resources, burnt a lot of money, and still missed obviously a large a pie of 300B opportunity.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108295/
A historical perspective on the discovery of statins
Cholesterol is essential for the functioning of all human organs, but it is nevertheless the cause of coronary heart disease. Over the course of nearly a century of investigation, scientists have developed several lines of evidence that establish the ...
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Open Longevity ENG

18 Aug 2018, 18:05

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242 0 0
Open Longevity ENG

18 Aug 2018, 18:05

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Steve Hill:
I propose that aging is a syndrome, a collection of hallmarks and symptoms frequently encountered together and associated with diseases. Given that we have demonstrated in the lab that many of these hallmarks are plastic and can be reversed, why do people still believe that aging is a one-way street?

Clearly, it is not as shown in cell line and animal experiments where various hallmarks have been reversed. This is why iPSC stem cells are possible and you can take cells from an aged person and make them functionally young again by reprogramming.

There are 9 aging hallmarks and there are solutions at varying stages of development right now. See the progress here: https://www.lifespan.io/the-rejuvenation-roadmap/
The Rejuvenation Roadmap | Lifespan.io
This curated database aims to compile the most promising therapies and technologies in development and chart their progress in one easy to read format. We have divided the projects into their corresponding aging hallmarks for ease of reference and clicking on each icon will take you to some more det...
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Open Longevity ENG

4 Aug 2018, 21:21

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131 0 0
Open Longevity ENG

4 Aug 2018, 21:21

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127 0 0
Open Longevity ENG

4 Aug 2018, 20:04

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Open Longevity ENG

1 Aug 2018, 16:51

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Also this October we are organizing our next school in Budva, Montenegro. The topic will be “Biohacking for life extension”.
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Open Longevity ENG

1 Aug 2018, 16:50

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Open Longevity ENG

1 Aug 2018, 16:50

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Alexander Kudryavtsev
This was the most interesting time in recent years! Professor Asakawa is one of the best scientists, who organize brilliant lab work and research at the University of Tokyo. Prasadi de Silva has very important studies for her doctorate degree. And I hope that our project Proteomarine will include the best practices for the development of the method of antigen-binding shark molecules and apply it for the treatment of age-related diseases. Bless God your laboratory and the University of Tokyo for what you are doing! I hope we have a great future for collaborate and an excellent project for Russia and for Japan!
有り難う御座います
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