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Correct Answer -C


ED50 refers to Effective Dose of a drug needed to produce a particular response in 50%
of population. It is a quantitative measure of the potency of a drug. Smaller the ED50 value,
more potent is the drug
Ref: Encyclopedia of Psychopharmacology By lan P. Stolerman, Volume 2, Page 456


3. Regarding efficacy and potency of a drug, all are true, EXCEPT: #NEET PG #FMGE #INICET #PYQ
Опрос
  •   a) In a clinical setup, efficacy is more important than potency
  •   b) In the log dose response curve, the height of the curve corresponds with efficacy
  •   c) ED50 of the drug corresponds to efficacy
  •   d) Drugs that produce a similar pharmacological effect can have different levels of efficacy
251 голосов


Answer -C
Ans. is 'c' i.e., Cytoplasmic vacuole
o Fatty changes occur in alcoholic steatosis (fatty liver). It is
manifested by appearence of lipid vacuole in the cytoplasm, which is
a sign of reversible injury.
○ Other three options (loss of cell membrane, nuclear karyolysis and
pyknosis) are signs of irreversible injur


Репост из: Pathology videos & books
32. The sign of reversible injury in a case of alcohol liver disease is #NEET PG #INICET #PYQ #FMGE
Опрос
  •   A) loss of cell membrane
  •   b) Nuclear karyolysis
  •   c) Cytoplasmic vacuole
  •   d) Pyknosis
8734 голосов


Correct Answer - C
Ans. is 'c" i.e., Dystrophic calcification


Calcification of soft tissues without any distrubance of calcium metabolism is called #NEET PG #FMGE #INICET #PYQ
Опрос
  •   a) lonotrophic calcification
  •   b) Monotrophic calcification
  •   c) Dystrophic calcification
  •   D)Calcium induced calcification
133 голосов


Correct Answer - B
Ans.is 'b'i.e., Atheromatous plaque
Dystrophic calcification
* When pathological calcification takes place in dead, dying or
degenerated tissue, it is called dystrophic calcification. o Calcium
metabolism is not altered and serum calcium level is normal.
Dystrophic calcification in Dystrophic calcification in
dead tissues
degenerated tissues
1.In caseous necrosis of 1. Atheromatous plague
tuberculosis
2. Monkeberg's sclerosis
(most common which may b& Psommama bodies
in lymph nodes)
4. Dens old scars
2.Chronic abscess in 5. Senile degenrated changes such
liquifactive necrosis
as in costal cartilage, tracheal,
3.Fungal granuloma
bronchial rings, Pineal gland in
4.Infarct
brain.
5.Thrombi 6. Heart valves damaged by
6.Haematomas
rheumatic fever.
7.Dead parasites-
Cystecercosis/Toxoplasma
Hydatid/Schistosoma
8.In fat necrosis of breast &
other tissues


DystrophicDystrophic calcification is seen in ? #NEET PG #FMGE #INICET #PYQ
Опрос
  •   a) Milk alkali syndrome
  •   b) Atheromatous plaque
  •   c) Hyperparathyroidism
  •   D)Vitamin A intoxication
318 голосов


Correct Answer - A
Ans. is 'a' i.e., Apaf 1
One of these proteins is cytochrome c, well known for its role in
mitochondrial respiration. In the cytosol, cytochrome C binds to a
protein called Apaf-1 (apoptosis activating factor-1), and the
complex activates caspase-9. (Bc1-2 and Bcl-x may also directly
inhibit Apaf-1 activation, and their loss from cells may permit
activation of Apaf-1


In apoptosis, cytochrome C acts through - #NEET PG #FMGE #INICET #PYQ
Опрос
  •   a) Apaf 1
  •   b) Bcl-2
  •   c) FADD
  •   d) TNF
214 голосов


Correct Answer -B
Ans. is 'b'i.e., Cell membrane
• yeline figures are cytoplasmic bodies composed of concentric
whorls of membranes, derived from damage cell membrane.
Myelin figures appear during reversible injury but they are more
pronounced in irreversible injury.


In cell death, myelin figures, are derived from- #NEET PG #FMGE #INICET #PYQ
Опрос
  •   a) Nucleus
  •   b) Cell membrane
  •   c) Cytoplasm
  •   d) Mitochondria
227 голосов


Correct Answer - A
Ans. is 'a' i.e., Coagulative necrosis
Coagulative necrosis
* This is most common type of necrosis.
* This type of necrosis is most frequently caused by sudden
cessation of blood flow (ischemia) in organs such as heart (MI),
Kidney (ATN), adrenal gland, and spleen.
Note: Brain is the only exception, i.e.,. It is the only solid organ in
which ischemia leads to liquifactive necrosis not coagulative
necrosis.
* It is also seen with other types of injury e.g.,liver necrosis in viral
hepatitis, Coagulative necrosis of skin after burns (Thermal injury).
Why there is predominant protein denaturation and no enzymatic
digestion ?
Hypoxia causes intracellular acidosis (has been explained earlier)
> .t pH results in denaturation ofproteins which includes not only
structural proteins hut also enzymes
So, there is no enzymatic digestion. o The necrotic cells retain their
cellular outline for several days.
Liquefactive necrosis
* It is the necrotic degradation of tissue that rapidly
undergo softening and liquefaction


MI is a type of- #NEET PG #FMGE #INICET #PYQ
Опрос
  •   Coagulative necrosis
  •   b) Liquefactive necrosis
  •   c) Caseous necrosis
  •   d) Fat necrosis
267 голосов


Correct Answer -D
Ans. is d i.e., Polymorphonuclear cells
Aschoff bodies
* Aschoff bodies are focal inflammatory lesions seen during acute
rheumatic fever
They consist of foci of swollen eosinophillic collagen surrounded by
Lymphocytes (primarily T cells)
Occasional plasma cells
Aschoff giant cells (macrophages of rheumatic fever)
Antitschkow cells
(Antischkow cells are modified macrophages with abundant
cytoplasm and central round to ovoid nuclei in which the chromatin
is disposed in the central, slender wavy ribbon like pattern-caterpillar
cells)
Histiocytes
Fibrobla


Репост из: Physiology
Growth hormone level decreased in #NEET PG #PYQ #INICET #FMGE
Опрос
  •   A) Hypoglycemia
  •   b) Fasting
  •   c) Sleep
  •   D)Exercise
4122 голосов


Репост из: Pathology videos & books
Which is not seen in Aschoff bodies - #NEET PG #INICET #PYQ #FMGE
Опрос
  •   a) Giant cells
  •   b) Aschoff cells
  •   c) Fibroblasts
  •   d) Polymorphonuclear cells
2629 голосов


Correct Answer - B Ans.is `b'i.e., Nicotine and carbon monoxide and tar Mechanisms for smoking-induced Coronary heart disease Carbon monoxide induces atherogenesis. Nicotine stimulation of adrenergic drive raising both BP and myocardial oxygen demand. Lipid metabolism with fall in protective high-density lipoproteins. Note .. Tar is associated with carcinogenesis (not atherosclerosis). But amongst the given options option b is the best answer as it consists of both nicotine and CO


Репост из: Obsterics & Gynecology
Most common site involved in genital TB #NEET PG #PYQ #INICET #FMGE
Опрос
  •   A) Fallopian tubes
  •   b) Endometrium
  •   c) Ovaries
  •   d) Vulvo - vaginal part
4162 голосов


Репост из: Biochemistry Videos & Books
The anticodon region is an important part of the #NEET PG #PYQ #INICET #FMGE
Опрос
  •   a) r-RNA
  •   b) m-RNa
  •   c) t-RNa
  •   D)hn rna
2066 голосов

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