Evaluation of Thrombocytosis:
1. CBC and blood smear should be obtained to evaluate platelet morphology and concurrent presence of anemia, leukemic blasts, or leukoerythroblastic features.
2. Patients with unexplained vasomotor symptoms (erythromelalgia, flushing, pruritus), constitutional symptoms, thrombosis at unusual or multiple sites, and/or splenomegaly should be evaluated for potential myeloproliferative neoplasm.
1. CBC and blood smear should be obtained to evaluate platelet morphology and concurrent presence of anemia, leukemic blasts, or leukoerythroblastic features.
2. Patients with unexplained vasomotor symptoms (erythromelalgia, flushing, pruritus), constitutional symptoms, thrombosis at unusual or multiple sites, and/or splenomegaly should be evaluated for potential myeloproliferative neoplasm.