⏳ Ozempic Extended Lifespan in Old Mice by 12%
Researchers in California started injecting female mice with semaglutide—the active ingredient in Ozempic—when the animals were 20 months old, roughly 60 in human years.
The median lifespan in the semaglutide group was 834 days, compared with 742 days in the control group, which received saline and unlimited standard chow. None of the animals were obese or diabetic.
Earlier work showed that calorie restriction can extend life and reduce some effects of aging—which is why the researchers wanted to test semaglutide: the drug curbs appetite without requiring constant willpower.
🔄 In a separate cohort, mice treated with semaglutide showed improvements in memory, coordination, and endurance, as well as better glucose control. They also had less chronic inflammation, fewer senescent cells, less DNA damage, and improved mitochondrial function.
In a separate experiment, researchers compared semaglutide with calorie restriction. The study lasted five months. One group received the drug, another had its food intake reduced by 24%, and a third ate without restrictions. The drug and calorie restriction produced similar results on many measures. But semaglutide performed better in tests of exploratory behavior, spatial memory, and glucose control.
🔍 What the paper doesn't have is a lifespan comparison between the drug and the diet. Independent scientists point to that gap; the authors say the experiment is underway.
Would you take Ozempic to live longer?
❤️ — Yes, if the effect holds up
🔥 — No, that sounds suspicious
@hiaimediaen
Researchers in California started injecting female mice with semaglutide—the active ingredient in Ozempic—when the animals were 20 months old, roughly 60 in human years.
The median lifespan in the semaglutide group was 834 days, compared with 742 days in the control group, which received saline and unlimited standard chow. None of the animals were obese or diabetic.
Earlier work showed that calorie restriction can extend life and reduce some effects of aging—which is why the researchers wanted to test semaglutide: the drug curbs appetite without requiring constant willpower.
🔄 In a separate cohort, mice treated with semaglutide showed improvements in memory, coordination, and endurance, as well as better glucose control. They also had less chronic inflammation, fewer senescent cells, less DNA damage, and improved mitochondrial function.
In a separate experiment, researchers compared semaglutide with calorie restriction. The study lasted five months. One group received the drug, another had its food intake reduced by 24%, and a third ate without restrictions. The drug and calorie restriction produced similar results on many measures. But semaglutide performed better in tests of exploratory behavior, spatial memory, and glucose control.
🔍 What the paper doesn't have is a lifespan comparison between the drug and the diet. Independent scientists point to that gap; the authors say the experiment is underway.
"I don't predict what the results might be. The results always surprise us," says study lead Danica Chen.
Would you take Ozempic to live longer?
❤️ — Yes, if the effect holds up
🔥 — No, that sounds suspicious
@hiaimediaen