🔖Practice question #62
A 17-year-old girl with a recent history of untreated sore throat presents to the physician with acute-onset fatigue, migratory joint pain, and subcutaneous nodules. She recalls a recent bout of sore throat for which she did not see a physician. A new heart murmur is heard on exam. The creation of the high-affinity targeted antibodies that are the culprit in this patient's condition requires T-cell mediated class-switching of B-cells. What is the structure of the molecule that presents the pathogenic antigen to T-cell in order to activate them?
A) A dimeric molecule held together by a J chain
B) A molecule composed of 2a and 2b homogenous peptides
C) A molecule composed of 3a chains and 1b-globulin
D) A molecule with 2H and 2L chains
E) A transmembrane molecule with a short cytoplasmic tail and 4 linearly arranged extracellular domains
Source: usmle_rx_qbank #2017 #immunology
A 17-year-old girl with a recent history of untreated sore throat presents to the physician with acute-onset fatigue, migratory joint pain, and subcutaneous nodules. She recalls a recent bout of sore throat for which she did not see a physician. A new heart murmur is heard on exam. The creation of the high-affinity targeted antibodies that are the culprit in this patient's condition requires T-cell mediated class-switching of B-cells. What is the structure of the molecule that presents the pathogenic antigen to T-cell in order to activate them?
A) A dimeric molecule held together by a J chain
B) A molecule composed of 2a and 2b homogenous peptides
C) A molecule composed of 3a chains and 1b-globulin
D) A molecule with 2H and 2L chains
E) A transmembrane molecule with a short cytoplasmic tail and 4 linearly arranged extracellular domains
Source: usmle_rx_qbank #2017 #immunology