#Remmber
#FUO was originally defined by Petersdorf and Beeson in 1961 as an illness of >3 weeks' duration with fever of >=38.30C (1010F) on two occasions and an uncertain diagnosis despite 1 week of inpatient evaluation.
👉The definition of #FUO has been further modified by the exclusion of immunocompromised patients,whose workup requires an entirely different diagnostic and therapeutic approach.
#FUO is now defined as:
🦠 Fever >38.30C (1010F) on at least two occasions
🦠 Illness duration of 3 weeks
🦠No known
immunocompromised state
🦠Diagnosis that remains uncertain after a thorough history-taking, physical examination,
👉the following obligatory investigations:
-(ESR
-CRP level;
-CBC
-electrolytes,
-creatinine,
-total protein, alkaline phosphatase, ALT, AST, LDH,
creatine kinase, ferritin,
-ANA,RF
-protein electrophoresis
-GUE
-blood cultures.
#FUO... Fever unkwon origin
#Harrison
@Medical_Channel_222