Correct Answer - B Ans.is `b'i.e., Nicotine and carbon monoxide and tar Mechanisms for smoking-induced Coronary heart disease Carbon monoxide induces atherogenesis. Nicotine stimulation of adrenergic drive raising both BP and myocardial oxygen demand. Lipid metabolism with fall in protective high-density lipoproteins. Note .. Tar is associated with carcinogenesis (not atherosclerosis). But amongst the given options option b is the best answer as it consists of both nicotine and CO